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Quantitative Cystinuria Test

Related Terms:

Urine Cystinuria

Type: Urine Cystinuria
Sample Types: Urine
Sample Processing
Cost: $160.00
Species and Breeds:
Canine - Any
Feline - Any

We do not provide kits. Please collect the sample following the sample collection and shipping instructions before ordering a test.

Description:

This test looks for the presence of cystine, ornithine, lysine, and arginine (COLA) in the urine through a quantitative LCMS test. Values obtained are normalized to urinary creatinine values. Cystine values for dogs that are higher than 179 nmol/mg or total COLA values higher than 700 nmol/mg show a high risk for forming urinary stones. Cystinuria is not as common in cats and standard values are not established yet. Reference intervals for cats are currently being investigated.

Clinical Signs:

Stranguria, hematuria, urinary blockage, bladder and kidney stones. Mostly in males.

Inheritance Mode:

Depends on the type of cystinuria - autosomal recessive or incomplete dominant - often sex-limited.

Results:

Negative - normal Borderline - mildly elevate cystine or COLA levels compared to normal/negative samples. Risk of stone formation is unknown. Positive - elevated urine cystine and/or COLA levels. Risk of cystine stone formation